Title : Physiological subtypes of gestational glucose intolerance and risk of adverse pregnancy outcomes.

Pub. Date : 2022 Feb

PMID : 34419453






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1 OBJECTIVE: We defined gestational glucose intolerance physiologic subtypes based on the presence of insulin resistance, insulin deficiency, or mixed pathophysiology, and aimed to determine if these subtypes are at differential risk for adverse outcomes. Glucose insulin Homo sapiens
2 We hypothesized that women with the insulin resistant subtype of gestational glucose intolerance would have the greatest risk of adverse pregnancy outcomes. Glucose insulin Homo sapiens
3 We applied homeostasis model assessment to fasting glucose and insulin levels at 16-20 weeks" gestation to assess insulin resistance and deficiency and used these measures to classify women with gestational glucose intolerance into subtypes. Glucose insulin Homo sapiens
4 We applied homeostasis model assessment to fasting glucose and insulin levels at 16-20 weeks" gestation to assess insulin resistance and deficiency and used these measures to classify women with gestational glucose intolerance into subtypes. Glucose insulin Homo sapiens
5 CONCLUSION: Insulin resistant gestational glucose intolerance is a high-risk subtype for adverse pregnancy outcomes. Glucose insulin Homo sapiens