Title : Novel ι-Carrageenan Tetrasaccharide Alleviates Liver Lipid Accumulation via the Bile Acid-FXR-SHP/PXR Pathway to Regulate Cholesterol Conversion and Fatty Acid Metabolism in Insulin-Resistant Mice.

Pub. Date : 2021 Sep 1

PMID : 34415766






4 Functional Relationships(s)
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1 Meanwhile, iotaCTs decreased the expression of PXR and SREBP1c and elevated the expression of PPARalpha and CPT1alpha via regulating the FXR-PXR-SREBP1c/PPARalpha signal to inhibit fatty acid synthesis and promote fatty acid beta-oxidation. Fatty Acids peroxisome proliferator activated receptor alpha Mus musculus
2 Meanwhile, iotaCTs decreased the expression of PXR and SREBP1c and elevated the expression of PPARalpha and CPT1alpha via regulating the FXR-PXR-SREBP1c/PPARalpha signal to inhibit fatty acid synthesis and promote fatty acid beta-oxidation. Fatty Acids peroxisome proliferator activated receptor alpha Mus musculus
3 Meanwhile, iotaCTs decreased the expression of PXR and SREBP1c and elevated the expression of PPARalpha and CPT1alpha via regulating the FXR-PXR-SREBP1c/PPARalpha signal to inhibit fatty acid synthesis and promote fatty acid beta-oxidation. Fatty Acids peroxisome proliferator activated receptor alpha Mus musculus
4 Meanwhile, iotaCTs decreased the expression of PXR and SREBP1c and elevated the expression of PPARalpha and CPT1alpha via regulating the FXR-PXR-SREBP1c/PPARalpha signal to inhibit fatty acid synthesis and promote fatty acid beta-oxidation. Fatty Acids peroxisome proliferator activated receptor alpha Mus musculus