Title : Genetic and Physiological Effects of Insulin on Human Urate Homeostasis.

Pub. Date : 2021

PMID : 34408667






1 Functional Relationships(s)
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1 Heterologous expression of individual urate transporters in Xenopus oocytes revealed that the (14C)-urate transport activities of GLUT9a, GLUT9b, OAT10, OAT3, OAT1, NPT1 and ABCG2 are directly activated by insulin signaling, through PI3 kinase (PI3K)/Akt, MEK/ERK and/or p38 MAPK. Uric Acid v-akt murine thymoma viral oncogene homolog 1 S homeolog Xenopus laevis