Pub. Date : 2021 Dec
PMID : 34402718
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Curcumin induces apoptosis and autophagy inhuman renal cell carcinoma cells via Akt/mTOR suppression. | Curcumin | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Likewise, AKT/mTOR proteins expression were significantly reduced while the autophagy-related proteins were significantly elevated following curcumin treatment. | Curcumin | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | In conclusion, the investigation demonstrated that curcumin suppressed ACHN cell viability, induced apoptosis and autophagy, through the suppression of AKT/mTOR pathway. | Curcumin | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | Use of curcumin to target AKT/mTOR pathway could be an effective treatment alternative for renal cell carcinoma. | Curcumin | AKT serine/threonine kinase 1 | Homo sapiens |