PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34402718-0 2021 Curcumin induces apoptosis and autophagy inhuman renal cell carcinoma cells via Akt/mTOR suppression. Curcumin 0-8 AKT serine/threonine kinase 1 Homo sapiens 80-83 34402718-10 2021 Likewise, AKT/mTOR proteins expression were significantly reduced while the autophagy-related proteins were significantly elevated following curcumin treatment. Curcumin 141-149 AKT serine/threonine kinase 1 Homo sapiens 10-13 34402718-12 2021 In conclusion, the investigation demonstrated that curcumin suppressed ACHN cell viability, induced apoptosis and autophagy, through the suppression of AKT/mTOR pathway. Curcumin 51-59 AKT serine/threonine kinase 1 Homo sapiens 152-155 34402718-13 2021 Use of curcumin to target AKT/mTOR pathway could be an effective treatment alternative for renal cell carcinoma. Curcumin 7-15 AKT serine/threonine kinase 1 Homo sapiens 26-29