Title : Dexamethasone may inhibit placental growth by blocking glucocorticoid receptors via phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin and reactive oxygen species/AMP-activated protein kinase signalling pathways in human placental JEG-3 cells.

Pub. Date : 2021 Oct

PMID : 34399087






1 Functional Relationships(s)
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Protein Name
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1 DEX blocked glucose uptake by downregulating GRalpha expression, which reduced GLUT1 and GLUT3 mRNA and protein expression, which, in turn, may have inhibited the PI3K/AKT/mTOR pathway and activated the ROS/AMPK pathway. ros protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens