Title : Rapid and Sensitive Quantification of Intracellular Glycyl-Sarcosine for Semi-High-Throughput Screening for Inhibitors of PEPT-1.

Pub. Date : 2021 Jul 3

PMID : 34371711






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The peptide transporter PEPT-1 (SLC15A1) plays a major role in nutritional supply with amino acids by mediating the intestinal influx of dipeptides and tripeptides generated during food digestion. Dipeptides solute carrier family 15 member 1 Homo sapiens
2 The dipeptide glycyl-sarcosine (Gly-Sar), which comprises an N-methylated peptide bond that increases stability against enzymatic degradation, is widely utilized for studying PEPT-1-mediated transport. Dipeptides solute carrier family 15 member 1 Homo sapiens