Title : Anisomycin protects against sepsis by attenuating IκB kinase-dependent NF-κB activation and inflammatory gene expression.

Pub. Date : 2021 Nov

PMID : 34353427






1 Functional Relationships(s)
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1 Furthermore, anisomycin attenuated nuclear factor (NF)-kappaB activation in LPS-induced macrophages, which correlated with the inhibition of phosphorylation of NF-kappaB-inducing kinase and IkappaB kinase, phosphorylation and IkappaBalpha proteolytic degradation, and NF-kappaB p65 subunit nuclear translocation. Anisomycin RELA proto-oncogene, NF-kB subunit Homo sapiens