Pub. Date : 2021 Jun
PMID : 34350255
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Curcumin exerts a protective effect on murine knee chondrocytes treated with IL-1beta through blocking the NF-kappaB/HIF-2alpha signaling pathway. | Curcumin | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 2 | Western blotting, immunofluorescence and immunohistochemistry experiments demonstrated that curcumin dramatically inhibited the activation of NF-kappaB/HIF-2alpha in chondrocytes treated with IL-1beta (P<0.01). | Curcumin | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 3 | Conclusions: Curcumin may have the potential to inhibit OA development, partly through suppressing the activation of the NF-kappaB/HIF-2alpha pathway. | Curcumin | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |