Title : Obesity-related IL-18 Impairs T-Regulatory Cell Function and Promotes Lung Ischemia-Reperfusion Injury.

Pub. Date : 2021 Nov 1

PMID : 34346860






2 Functional Relationships(s)
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1 RESULTS: We identified increased levels of IL-18 as a previously unrecognized mechanism that impairs Treg suppressive function in obese individuals. treg interleukin 18 Mus musculus
2 The IL-18 driven impairment in Treg suppressive function pre-transplant was associated with increased risk and severity of PGD in clinical lung transplant recipients. treg interleukin 18 Mus musculus