Title : AKT1/FOXP3 axis-mediated expression of CerS6 promotes p53 mutant pancreatic tumorigenesis.

Pub. Date : 2021 Dec 1

PMID : 34343636






1 Functional Relationships(s)
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1 The AKT1/FOXP3 axis mediated the CerS6 expression and promoted p53 mutant pancreatic tumorigenesis by producing excessive C16-ceramide, which induced the accumulation of mutant p53. N-palmitoylsphingosine AKT serine/threonine kinase 1 Homo sapiens