Title : Design, synthesis, docking, ADMET studies, and anticancer evaluation of new 3-methylquinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers.

Pub. Date : 2021 Dec

PMID : 34340610






1 Functional Relationships(s)
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1 Compound 27a was the most potent VEGFR-2 inhibitor with IC50 of 3.2 nM very close to positive control sorafenib (IC50 = 3.12 nM). Sorafenib kinase insert domain receptor Homo sapiens