Pub. Date : 2021 Sep
PMID : 34322995
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of Janus Kinase 1 synergizes docetaxel sensitivity in prostate cancer cells. | Docetaxel | Janus kinase 1 | Homo sapiens |
| 2 | We demonstrated that depletion of endogenous JAK1 enhanced docetaxel-induced apoptosis in PCa cells. | Docetaxel | Janus kinase 1 | Homo sapiens |
| 3 | Furthermore, inhibition of JAK1/2 by baricitinib and ruxolitinib synergizes docetaxel sensitivity in both androgen receptor (AR)-negative DU145 and PC3 cells, but not in the AR-positive LNCaP cells. | Docetaxel | Janus kinase 1 | Homo sapiens |