Title : Combined computational and cellular screening identifies synergistic inhibition of SARS-CoV-2 by lenvatinib and remdesivir.

Pub. Date : 2021 Jul

PMID : 34319869






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Lenvatinib is a broadly-acting host receptor tyrosine kinase (RTK) inhibitor, but the synergistic effect with remdesivir was not observed with other approved RTK inhibitors (such as pazopanib or sunitinib), suggesting that the mechanism-of-action is independent of host RTKs. remdesivir ret proto-oncogene Homo sapiens