Title : A glutaminyl cyclase-catalyzed α-synuclein modification identified in human synucleinopathies.

Pub. Date : 2021 Sep

PMID : 34309760






1 Functional Relationships(s)
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1 We argue that glutaminyl cyclase (QC) may catalyze the pyroglutamate (pGlu)79-alpha-synuclein formation and, thereby, contribute to enhanced aggregation and compromised degradation of alpha-synuclein in human synucleinopathies. Pyrrolidonecarboxylic Acid synuclein alpha Homo sapiens