Pub. Date : 2021
PMID : 34306367
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CHOP overexpression sensitizes human non-small cell lung cancer cells to cisplatin treatment by Bcl-2/JNK pathway. | Cisplatin | BCL2 apoptosis regulator | Homo sapiens |
| 2 | CHOP increased the therapeutic effect of cisplatin on NSCLC cells through the Bcl-2/JNK pathway. | Cisplatin | BCL2 apoptosis regulator | Homo sapiens |
| 3 | In summary, CHOP regulated cisplatin resistance in cells of NSCLC by promoting the expression of apoptotic proteins and inhibiting the Bcl-2/JNK signaling pathway, indicating the antitumor effects of CHOP. | Cisplatin | BCL2 apoptosis regulator | Homo sapiens |