Title : The Associations between COMT and MAO-B Genetic Variants with Negative Symptoms in Patients with Schizophrenia.

Pub. Date : 2021 Jul 8

PMID : 34287249






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Catechol-O-methyltransferase (COMT) and monoamine oxidase type B (MAO-B) degrade dopamine and affect its neurotransmission. Dopamine catechol-O-methyltransferase Homo sapiens
2 Catechol-O-methyltransferase (COMT) and monoamine oxidase type B (MAO-B) degrade dopamine and affect its neurotransmission. Dopamine catechol-O-methyltransferase Homo sapiens
3 These findings suggest that higher dopamine degradation, associated with COMT and MAO-B genetic variants, is associated with a sex-specific increase in the severity of negative symptoms in schizophrenia patients. Dopamine catechol-O-methyltransferase Homo sapiens