Title : Activation of the aryl hydrocarbon receptor by 3-methylcholanthrene, but not by indirubin, suppresses mammosphere formation via downregulation of CDC20 expression in breast cancer cells.

Pub. Date : 2021 Sep 17

PMID : 34280616






1 Functional Relationships(s)
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1 We reported previously that 3-methylcholanthrene (3MC), an exogenous AhR agonist, inhibited tumorsphere (mammosphere) formation from breast cancer cell lines, while the endogenous AhR agonist, indirubin, very weakly inhibited this process. indirubin aryl hydrocarbon receptor Homo sapiens