Title : PBDEs affect inflammatory and oncosuppressive mechanisms via the EZH2 methyltransferase in airway epithelial cells.

Pub. Date : 2021 Oct 1

PMID : 34273373






1 Functional Relationships(s)
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1 SIGNIFICANCE: PBDE inhalation might promote inflammation/cancer via EZH2 methyltransferase activity and H3K27me3, k-RAS and ERk1/2 involvement, generating adverse health outcomes of the human lung. pentabromodiphenyl ether KRAS proto-oncogene, GTPase Homo sapiens