Pub. Date : 2021 Sep 1
PMID : 34261222
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The results indicate that PFOS exposure significantly up-regulated the expressions of StAR, CYP11A1 and 3beta-HSD, while CYP17A1 and 17beta-HSD were down-regulated, thus contributing to the elevated progesterone and testosterone levels. | perfluorooctane sulfonic acid | cytochrome P450, family 11, subfamily a, polypeptide 1 | Rattus norvegicus |
| 2 | It was found that H3K18ac was augmented in Cyp11a1 promoter, and H3K9ac was increased in Hsd3b after PFOS exposure, which is proposed to result in the activation of CYP11A1 and 3beta-HSD, respectively. | perfluorooctane sulfonic acid | cytochrome P450, family 11, subfamily a, polypeptide 1 | Rattus norvegicus |