Protein Name | cytochrome P450, family 11, subfamily a, polypeptide 1 |
---|---|
Organism | Rattus norvegicus |
Gene ID | 29680 |
Gene Symbol | Cyp11a1 |
UniProt | P14137 (CP11A_RAT) |
Relationships |
Total Number of functionally related compound(s) :
208
Total Number of Articles : 341 |
Description |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
Gene Summary |
Enables cholesterol binding activity and cholesterol monooxygenase (side-chain-cleaving) activity. Involved in several processes, including nervous system development; response to vitamin; and steroid biosynthetic process. Located in mitochondrial crista and perikaryon. Biomarker of several diseases, including glucose metabolism disease (multiple); hypertension; nephrosis; sciatic neuropathy; and status epilepticus. Human ortholog(s) of this gene implicated in congenital adrenal hyperplasia and congenital adrenal insufficiency. Orthologous to human CYP11A1 (cytochrome P450 family 11 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022] |
synonyms |
|
Properties | |