Title : Gleevec and Rapamycin Synergistically Reduce Cell Viability and Inhibit Proliferation and Angiogenic Function of Mouse Bone Marrow-Derived Endothelial Progenitor Cells.

Pub. Date : 2021

PMID : 34247157






1 Functional Relationships(s)
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1 Mechanistically, Gleevec, but not rapamycin, induced a significant elevation in caspase-3 activity in EPCs, and it attenuated the expression of the endothelial protein marker platelet-derived growth factor receptor alpha. Imatinib Mesylate caspase 3 Mus musculus