Title : The effect of CYP2D6 and CYP2C9 gene polymorphisms on the efficacy and safety of the combination of tramadol and ketorolac used for postoperative pain management in patients after video laparoscopic cholecystectomy.

Pub. Date : 2021 Jul 12

PMID : 34246203






2 Functional Relationships(s)
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1 The aims of the present study are to assess the possible association of CYP2D6 and CYP2C9 polymorphisms with the efficacy and safety of tramadol and ketorolac in postoperative pain. Tramadol cytochrome P450 family 2 subfamily C member 9 Homo sapiens
2 CONCLUSIONS: CYP2D6 and CYP2C9 can predict analgesic effectiveness of tramadol and ketorolac. Tramadol cytochrome P450 family 2 subfamily C member 9 Homo sapiens