Pub. Date : 2021 Jul
PMID : 34243628
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In the acrylamide group, malondialdehyde (MDA), tumour necrosis factor-alpha (TNF-alpha), and interleukin-1 beta (IL-1beta) levels were found to be high, total glutathione (tGSH) levels were found to be low, and there was severe interstitial haemorrhage; additionally, tubular necrosis, tubular atrophy, leucocyte infiltration, and glomerular structures with expanded Bowman"s space were observed. | Acrylamide | tumor necrosis factor | Rattus norvegicus |
2 | This suggests that Taxifolin would prevent kidney tissue from acrylamide-induced damage would be effective in treating acrylamide-induced nephrotoxicity, inhibiting the increase of MDA, IL-1beta and TNF-alpha, and decreasing tGSH associated with acrylamide. | Acrylamide | tumor necrosis factor | Rattus norvegicus |