Title : Differential Impact of Clinical and Genetic Factors on High Platelet Reactivity in Patients with Coronary Artery Disease Treated with Clopidogrel and Prasugrel.

Pub. Date : 2021 Jul 8

PMID : 34234079






2 Functional Relationships(s)
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Protein Name
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1 Although the number of CYP2C19 loss-of-function alleles was clearly associated with a likelihood of HPR with clopidogrel, P2Y12 reactivity units with prasugrel treatment were also significantly and progressively higher in patients with more CYP2C19 loss-of-function alleles. Prasugrel Hydrochloride purinergic receptor P2Y12 Homo sapiens
2 CONCLUSIONS: Clinical and genetic factors had a differential effect on a P2Y12 inhibitor reactivity with clopidogrel and prasugrel in patients with coronary artery disease. Prasugrel Hydrochloride purinergic receptor P2Y12 Homo sapiens