Title : Glutathione- and apolipoprotein E-grafted liposomes to regulate mitogen-activated protein kinases and rescue neurons in Alzheimer's disease.

Pub. Date : 2021 Aug

PMID : 34225874






3 Functional Relationships(s)
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1 Phosphatidylcholine (PC)-liposomes carrying curcumin (CURC), quercetin (QU), epigallocatechin gallate (EGCG) and rosmarinic acid (RA) with crosslinked glutathione (GSH) and apolipoprotein E (ApoE) were fabricated to recognize brain microvascular endothelial cells and amyloid beta (Abeta), and reduce tau protein hyperphosphorylation for AD management. rosmarinic acid apolipoprotein E Homo sapiens
2 The triple targeting liposomes boosted the capability of CURC, QU, EGCG and RA for crossing the BBB with the assistance of grafted GSH and ApoE and docking Abeta around SK-N-MC cells using ApoE and PC. rosmarinic acid apolipoprotein E Homo sapiens
3 The triple targeting liposomes boosted the capability of CURC, QU, EGCG and RA for crossing the BBB with the assistance of grafted GSH and ApoE and docking Abeta around SK-N-MC cells using ApoE and PC. rosmarinic acid apolipoprotein E Homo sapiens