Title : IRE1-mTOR-PERK Axis Coordinates Autophagy and ER Stress-Apoptosis Induced by P2X7-Mediated Ca2+ Influx in Osteoarthritis.

Pub. Date : 2021

PMID : 34222263






1 Functional Relationships(s)
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1 To further investigate the role of P2X7 in OA, we injected mTOR antagonist rapamycin or P2X7 antagonist A740003 into the knee joints of ACLT rats. Sirolimus mechanistic target of rapamycin kinase Rattus norvegicus