Title : Dual targeting of MEK and PI3K effectively controls the proliferation of human EGFR-TKI resistant non-small cell lung carcinoma cell lines with different genetic backgrounds.

Pub. Date : 2021 Jul 1

PMID : 34210314






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 H460 cells with K-RAS and PIK3CA mutation were most sensitive to MEK162 and BKM120 combinations. NVP-BKM120 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Homo sapiens