Title : Alantolactone Suppresses Proliferation and the Inflammatory Response in Human HaCaT Keratinocytes and Ameliorates Imiquimod-Induced Skin Lesions in a Psoriasis-Like Mouse Model.

Pub. Date : 2021 Jun 25

PMID : 34202301






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1 Furthermore, alantolactone treatment in mice significantly alleviated the severity of skin lesions (erythema, scaling and epidermal thickness, and inflammatory cell infiltration) and decreased the mRNA expression of inflammatory cytokines (e.g., TNF-alpha, IL-6, IL-1beta, IL-8, IL-17A, and IL-23) in an IMQ-induced-like mouse model. alantolactone interleukin 6 Mus musculus