Pub. Date : 1988 Sep
PMID : 3419426
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of glucokinase by alloxan through interaction with SH groups in the sugar-binding site of the enzyme. | Sugars | glucokinase | Homo sapiens |
| 2 | It is concluded, therefore, that the mechanism of inhibition of glucokinase by alloxan is a reaction of alloxan with two adjacent SH groups in the depth of the sugar-binding site of the glucokinase, with formation of a disulfide bond and concomitant inactivation of the enzyme. | Sugars | glucokinase | Homo sapiens |
| 3 | It is concluded, therefore, that the mechanism of inhibition of glucokinase by alloxan is a reaction of alloxan with two adjacent SH groups in the depth of the sugar-binding site of the glucokinase, with formation of a disulfide bond and concomitant inactivation of the enzyme. | Sugars | glucokinase | Homo sapiens |