Title : Nanomolar inhibition of human OGA by 2-acetamido-2-deoxy-d-glucono-1,5-lactone semicarbazone derivatives.

Pub. Date : 2021 Nov 5

PMID : 34186233






1 Functional Relationships(s)
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Protein Name
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1 O-GlcNAcylation is a dynamic post-translational modification mediated by O-linked beta-N-acetylglucosamine transferase (OGT) and O-GlcNAc hydrolase (OGA), that adds or removes a single beta-N-acetylglucosamine (GlcNAc) moiety to or from serine/threonine residues of nucleocytosolic and mitochondrial proteins, respectively. Serine O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens