Title : Granzyme B prevents aberrant IL-17 production and intestinal pathogenicity in CD4+ T cells.

Pub. Date : 2021 Sep

PMID : 34183776






1 Functional Relationships(s)
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1 It has been well-documented that granzyme B, a potent serine protease involved in cell-mediated cytotoxicity, is readily expressed by certain CD4+ T cells, such as regulatory T cells and CD4+CD8alphaalpha+ intestinal intraepithelial lymphocytes, both of which display cytotoxicity associated with granzyme B. Serine granzyme B Mus musculus