Title : Dexmedetomidine post-conditioning attenuates cerebral ischemia following asphyxia cardiac arrest through down-regulation of apoptosis and neuroinflammation in rats.

Pub. Date : 2021 Jun 28

PMID : 34182937






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1 In addition, dexmedetomidine post-conditioning attenuated the serum levels of the pro-inflammatory cytokine tumor necrosis factor (TNF)-alpha at 2 h, as well as interleukin IL-1beta at 2, 24, and 48 h. TUNEL staining showed that the number of apoptotic cells in the dexmedetomidine post-conditioning group was significantly reduced compared with the control group. Dexmedetomidine interleukin 1 alpha Rattus norvegicus
2 In addition, dexmedetomidine post-conditioning attenuated the serum levels of the pro-inflammatory cytokine tumor necrosis factor (TNF)-alpha at 2 h, as well as interleukin IL-1beta at 2, 24, and 48 h. TUNEL staining showed that the number of apoptotic cells in the dexmedetomidine post-conditioning group was significantly reduced compared with the control group. Dexmedetomidine interleukin 1 alpha Rattus norvegicus