Title : HDAC6 inhibitor ACY1215 inhibits the activation of NLRP3 inflammasome in acute liver failure by regulating the ATM/F-actin signalling pathway.

Pub. Date : 2021 Aug

PMID : 34180140






1 Functional Relationships(s)
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1 The ATM inhibitor KU55933 could decrease the level of ATM, gamma-H2AX, Chk2, p53, p21, F-actin and vinculin in ALF with ACY1215 pretreatment. 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one checkpoint kinase 2 Mus musculus