Title : Design and synthesis of Grp94 selective inhibitors based on Phe199 induced fit mechanism and their anti-inflammatory effects.

Pub. Date : 2021 Nov 5

PMID : 34174740






2 Functional Relationships(s)
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1 In a dextran sulfate sodium (DSS)-induced mouse model of ulcerative colitis (UC), compound 4 showed anti-inflammatory property and reduced the levels of pro-inflammatory cytokines (TNF-alpha and IL-6). Dextran Sulfate interleukin 6 Mus musculus
2 In a dextran sulfate sodium (DSS)-induced mouse model of ulcerative colitis (UC), compound 4 showed anti-inflammatory property and reduced the levels of pro-inflammatory cytokines (TNF-alpha and IL-6). Dextran Sulfate interleukin 6 Mus musculus