Title : Irbesartan suppresses lipopolysaccharide (LPS)-induced blood-brain barrier (BBB) dysfunction by inhibiting the activation of MLCK/MLC.

Pub. Date : 2021 Sep

PMID : 34174702






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The results of our mouse model study revealed that Irbesartan could reduce BBB permeability, restore the expression of Occludin, and suppress the expression of inflammatory mediators, including interleukin-6, monocyte chemoattractant protein-1, and intercellular adhesion molecule-1. Irbesartan interleukin 6 Mus musculus