Title : Lipopolysaccharide-induced inflammation in human peritoneal mesothelial cells is controlled by ERK1/2-CDK5-PPARĪ³ axis.

Pub. Date : 2021 May

PMID : 34164484






1 Functional Relationships(s)
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1 Further, ERK1/2 inhibition by AZD0364 prevented IL-1beta, IL-6, IL-12, and CDK5 expression, as well as activation of ERK1/2 and phosphorylation of PPARgamma, induced by LPS. N-(3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl)-2-methyl-2-((5-(trifluoromethyl)pyridin-2-yl)oxy)propanamide cyclin dependent kinase 5 Homo sapiens