Title : Epidermal growth factor receptor and integrins meet redox signaling through P66shc and Rac1.

Pub. Date : 2021 Oct

PMID : 34157521






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Integrin-induced activation of EGFR and subsequent tyrosine phosphorylation of a class of acceptor sites on EGFR leads to alignment and tyrosine phosphorylation of Shc, PLCgamma, the p85 subunit of PI-3 K, and Cbl, followed by activation of the downstream targets Erk and Akt/PKB. Tyrosine SHC adaptor protein 1 Homo sapiens
2 Integrin-induced activation of EGFR and subsequent tyrosine phosphorylation of a class of acceptor sites on EGFR leads to alignment and tyrosine phosphorylation of Shc, PLCgamma, the p85 subunit of PI-3 K, and Cbl, followed by activation of the downstream targets Erk and Akt/PKB. Tyrosine SHC adaptor protein 1 Homo sapiens