Title : NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals.

Pub. Date : 1979 Feb

PMID : 34156






1 Functional Relationships(s)
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1 With NADPH as the electron donor, rat liver NADPH cytochrome P-450 reductase (NADPH:ferricytochrome oxidoreductase, EC 1.6.2.4) catalyzes the single-electron reduction of several quinone antibiotics to a semiquinone or free radical state. quinone cytochrome p450 oxidoreductase Rattus norvegicus