Protein Name cytochrome p450 oxidoreductase
Organism Rattus norvegicus
Gene ID 29441
Gene Symbol

Por

UniProt P00388 (NCPR_RAT)
Relationships Total Number of functionally related compound(s) : 403
Total Number of Articles : 357
Description

cytochrome p450 oxidoreductase

Gene Summary

Enables several functions, including iron-cytochrome-c reductase activity; nucleotide binding activity; and oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. Involved in several processes, including cellular response to follicle-stimulating hormone stimulus; nitric oxide catabolic process; and oxoacid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in Antley-Bixler syndrome with disordered steroidogenesis; congenital adrenal hyperplasia; and cytochrome P450 oxidoreductase deficiency. Orthologous to human POR (cytochrome p450 oxidoreductase). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • NADPH--cytochrome P450 reductase
  • CPR
  • P450 (cytochrome) oxidoreductase
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Properties