Protein Name cytochrome p450 oxidoreductase
Organism Rattus norvegicus
Gene ID 29441
Gene Symbol

Por

UniProt P00388 (NCPR_RAT)
Relationships Total Number of functionally related compound(s) : 403
Total Number of Articles : 357
Description

cytochrome p450 oxidoreductase

Gene Summary

Enables several functions, including iron-cytochrome-c reductase activity; nucleotide binding activity; and oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. Involved in several processes, including cellular response to hormone stimulus; negative regulation of hydrolase activity; and positive regulation of steroid biosynthetic process. Located in membrane and mitochondrion. Human ortholog(s) of this gene implicated in congenital adrenal hyperplasia and cytochrome P450 oxidoreductase deficiency. Orthologous to human POR (cytochrome p450 oxidoreductase). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • NADPH--cytochrome P450 reductase
  • CPR
  • P450 (cytochrome) oxidoreductase
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Properties