Title : Pdcd10-Stk24/25 complex controls kidney water reabsorption by regulating Aqp2 membrane targeting.

Pub. Date : 2021 Jun 22

PMID : 34156031






1 Functional Relationships(s)
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1 Treatment with Erlotinib, a tyrosine kinase inhibitor promoting exocytosis and inhibiting endocytosis, normalized the expression level and membrane abundance of Aqp2 protein, and partially rescued the water reabsorption defect observed in the Pdcd10-deficient mice. Erlotinib Hydrochloride aquaporin 2 Mus musculus