Pub. Date : 2021 Oct 1
PMID : 34153408
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nicotine facilitates pancreatic fibrosis by promoting activation of pancreatic stellate cells via alpha7nAChR-mediated JAK2/STAT3 signaling pathway in rats. | Nicotine | Janus kinase 2 | Rattus norvegicus |
| 2 | Moreover, nicotine also activated the alpha7nAChR-mediated JAK2/STAT3 signaling pathway in rPSCs. | Nicotine | Janus kinase 2 | Rattus norvegicus |
| 3 | SIGNIFICANCE: Our finding in this research suggests that nicotine facilitates pancreatic fibrosis by promoting activation of pancreatic stellate cells via alpha7nAChR-mediated JAK2/STAT3 signaling pathway in rats, partly revealing the mechanism of smoking on chronic pancreatitis. | Nicotine | Janus kinase 2 | Rattus norvegicus |