Pub. Date : 2021
PMID : 34149427
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We demonstrated that celastrol inhibited the receptor activator of nuclear factor kappaB ligand-induced osteoclastogenesis and the bone resorptive function of osteoclasts in vitro by inhibiting the activation of transforming growth factor beta-activated kinase 1-mediated NF-kappaB and mitogen-activated protein kinase signaling pathways and downregulating osteoclastogenesis marker-related genes. | celastrol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |