Pub. Date : 2021 Sep 15
PMID : 34147475
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Importantly, vitamin D3 treatment increased the expression of the vitamin D receptor and inhibited Transforming growth factor-beta1 (TGF-beta1)/Smad3 signaling pathway in rats kidneys with chronic kidney disease. | Cholecalciferol | vitamin D receptor | Rattus norvegicus |
2 | Mechanistically, the upregulation of TGF-beta1 and phosphorylation of Smad3 induced by vitamin D3 was reversed by activation of the vitamin D receptor. | Cholecalciferol | vitamin D receptor | Rattus norvegicus |