Pub. Date : 2021 Apr
PMID : 34103445
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | STRESS-AFFECTED AKT/MTOR PATHWAY UPREGULATED BY LONG-TERM CREATINE INTRAPERITONEAL ADMINISTRATION. | Creatine | mechanistic target of rapamycin kinase | Homo sapiens |
| 2 | Since the central regulatory substance in energy metabolism is the signalling molecule mTOR, we studied its quantitative changes under long-term disruption of circadian rhythm and exogenous creatine administration. | Creatine | mechanistic target of rapamycin kinase | Homo sapiens |
| 3 | The results revealed that Creatine"s exogenous supplementation increases phosphorylated mTOR and its activator - Akt. | Creatine | mechanistic target of rapamycin kinase | Homo sapiens |
| 4 | Consequently, it can be assumed that Creatine performs its positive role in hippocampal cells" energy metabolism via its modulatory effects on the PI3K/Akt/mTOR signalling pathway. | Creatine | mechanistic target of rapamycin kinase | Homo sapiens |