Title : Vitamin D3 attenuates doxorubicin-induced senescence of human aortic endothelial cells by upregulation of IL-10 via the pAMPKα/Sirt1/Foxo3a signaling pathway.

Pub. Date : 2021

PMID : 34101754






2 Functional Relationships(s)
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1 Vitamin D3 attenuates doxorubicin-induced senescence of human aortic endothelial cells by upregulation of IL-10 via the pAMPKalpha/Sirt1/Foxo3a signaling pathway. Cholecalciferol sirtuin 1 Homo sapiens
2 We further show the protective effects of vitamin D3 are mediated by the upregulation of IL-10 and FOXO3a expression through fine modulation of pAMPKalpha/SIRT1/FOXO3a complex activity. Cholecalciferol sirtuin 1 Homo sapiens