Title : High throughput screening identifies SOX2 as a super pioneer factor that inhibits DNA methylation maintenance at its binding sites.

Pub. Date : 2021 Jun 7

PMID : 34099689






1 Functional Relationships(s)
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1 Finally, while most SPFs induce TET-dependent active DNA demethylation, SOX2 binding leads to passive demethylation, an activity enhanced by the co-binding of OCT4. tetramethylenedisulfotetramine POU class 5 homeobox 1 Homo sapiens