Title : Systematic Pharmacology Reveals the Antioxidative Stress and Anti-Inflammatory Mechanisms of Resveratrol Intervention in Myocardial Ischemia-Reperfusion Injury.

Pub. Date : 2021

PMID : 34093716






2 Functional Relationships(s)
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1 Compared with the MIRI group, serum IL-1beta, TNF-alpha, and IL-6 in the resveratrol group was significantly reduced (P < 0.05), and myocardial tissue TLR4, NF-kappaB p65, IL-1beta, IL-6, and TNF-alpha mRNA and protein expressions were significantly reduced (P < 0.05). Resveratrol interleukin 6 Rattus norvegicus
2 Compared with the MIRI group, serum IL-1beta, TNF-alpha, and IL-6 in the resveratrol group was significantly reduced (P < 0.05), and myocardial tissue TLR4, NF-kappaB p65, IL-1beta, IL-6, and TNF-alpha mRNA and protein expressions were significantly reduced (P < 0.05). Resveratrol interleukin 6 Rattus norvegicus