Title : Remdesivir Alleviates Acute Kidney Injury by Inhibiting the Activation of NLRP3 Inflammasome.

Pub. Date : 2021

PMID : 34093539






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Mechanically, RDV effectively suppressed the activities of nuclear transcription factor (NF)-kappaB, mitogen-activated protein kinase (MAPK), which further led to the reduction of the inflammasome genes of NLRP3 transcription, limiting the activation of NLRP3 inflammasome in vivo and in vitro. remdesivir nuclear factor kappa B subunit 1 Homo sapiens