Title : In vitro and in vivo tenocyte-protective effectiveness of dehydroepiandrosterone against high glucose-induced oxidative stress.

Pub. Date : 2021 Jun 5

PMID : 34090401






2 Functional Relationships(s)
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1 RESULTS: In rat tenocytes, DHEA decreased the expression of NOX1 and IL-6, ROS accumulation, and apoptotic cells. Dehydroepiandrosterone interleukin 6 Rattus norvegicus
2 In the diabetic rat Achilles tendon, NOX1 protein expression and mRNA expression of NOX1, IL-6, MMP-2, TIMP-2, and type III collagen were significantly lower while type I collagen expression was significantly higher in the DHEA group than in the control group. Dehydroepiandrosterone interleukin 6 Rattus norvegicus